Pharmacokinetic Study of Biotransformation Products from an Anxiolytic Fraction of Tilia americana
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چکیده
منابع مشابه
Pharmacokinetic Study of Biotransformation Products from an Anxiolytic Fraction of Tilia americana.
An anxiolytic fraction of Tilia americana standardized in tiliroside, rutin, quercitrin, quercetin glucoside, and kaempferol was obtained. After oral administration of the fraction, the above-mentioned flavonoids were not detected in plasma over 24 h. However, meta and para hydroxyphenylacetic acid and dihydroxyphenylacetic acid (m-HPAA, p-HPAA and DOPAC) were monitored. These are the biotransf...
متن کاملAnxiolytic and sedative-like effects of flavonoids from Tilia americana var. mexicana: GABAergic and serotonergic participation
Introduction The inflorescences of Tilia americana var. mexicana are used as an infusion in Mexican traditional medicine due to their tranquilizing effects; however, pharmacological and phytochemical studies of the leaves are lacking. Objective In this research, the anxiolytic and sedative-like efficacy of the Tilia americana var. mexicana leaves was compared to that obtained with its infloresc...
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The endosperm cells of the American basswood Tilia americana are favorable experimental material for investigating the birefringence of living plant spindles and anaphase movement of chromosomes. The behavior of the chromosomes in anaphase and the formation of the phragmoplast are unique. The numerous (3 n equals 123), small chromosomes move in precise, parallel rows until midanaphase when they...
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15 صفحه اولEffect of Standardized Fractions and Tiliroside from Leaves of Tilia americana on Depression Tests in Mice
Depression affects more than 300 million people worldwide, represents one of the leading causes of disability worldwide. Treatment is based on the use of tricyclic antidepressant, selective serotonin reuptake inhibitors, between others; that although are clinically effective has a delayed onset activity and produce important side effects. Medicinal plants are presented as a source of study in t...
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ژورنال
عنوان ژورنال: Molecules
سال: 2017
ISSN: 1420-3049
DOI: 10.3390/molecules22081260